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Break-through in mitochondrial gene editing

Mitochondria, the organelles that produce most of a cell’s energy, are distinguished from other organelles by having their own genetic information which is independent of the nucleus. The mitochondrial genome encodes for only 13 proteins, but these proteins are not only very important for energy generation; mutations in these genes are known to be responsible for a number of inherited diseases and they have been implicated in metabolic diseases, aging and neurodegeneration.