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If your dog needs itch relief, your vet may now offer a drug called Cytopoint. Cytopoint, produced by Zoetis Inc. and available in the US since early 2018, is an engineered (caninized) monoclonal antibody directed against interleukin-31. Interleukin-31 has been shown to induce atopic dermatitis in dogs in laboratory studies and Cytopoint can cause a dramatic reduction the symptoms of atopic dermatitis. Cytopoint is administered by subcutaneous injection. Your dog may not be too keen on needles. However, a single dose of Cytopoint can control the itching for up to 8 weeks and that may be much better than a steroid pill every day. So what’s next? Monoclonals for the birds?