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Chemotherapy leads to drug resistance in tumor blood vessels

Scientists at Hokkaido University have published research on the effects of chemotherapy on the cells that line the blood vessels inside tumors. They found that, in response to first-line chemotherapy, these tumor endothelial cells (TEC) can become drug-resistant, which allows the tumors themselves to survive chemotherapy and metastasize.

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CRISPRing out Host Cell Proteins

In a recent Nature Communications paper titled "Multiplex secretive engineering enhances recombinant protein production and purity", scientists from the Technical University of Denmark and the University of California, San Diego, describe their work to create a...

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Clinical trials in the time of COVID-19

FDA has issued guidelines  for the conduct of clinical trials during the COVID-19 pandemic. “With this guidance issued today, the FDA is helping industry and investigators navigate the COVID-19 pandemic and help assess how to move forward with critical clinical...

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The infinite Monkey Cage

To provide some diversion during these trying times, a colleague recommended ‘The infinite Monkey Cage’. Extremely funny British science podcast. There are more than 10 seasons for your pleasure. You will learn and you will laugh. If you like Monty Python you are on...

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COVID-19 vaccines

Hope for containing the COVI-19 pandemic rests on the develop of an effective vaccine for SARS-CoV-2. Recently we found an interesting list of 16 ongoing efforts to develop a SARS-CoV-2 vaccine in the magazine The Scientist. These vaccines vary considerably in their...

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