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Biologics

mAbs: The Rory Story

My family’s dog, Rory, has always been weird. He will start screaming if, while running around the house like a maniac, he accidentally stubs his toe. He loves eating carrots. He gets jealous if two people are hugging and he isn’t included. He will only lie down on the softest pillow on the couch. He likes to sit on our laps after we’ve eaten dinner and flops over with wild abandon, confident that someone will catch him before he falls. He has been known to collect items such as books, shoes, and pencils in a particular corner of the living room. He is exceptionally food motivated and sometimes obnoxious in his relentless pursuit of affection.

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Super-antibodies against SARS-CoV-2 show promising results in animals

If you’ve been following biomedical news on the novel coronavirus over the last several months, there’s a good chance you’ve heard about the potential for antibodies from recovered COVID-19 patients (convalescent antibodies) to help fight the virus and provide temporary immunity to healthcare workers and other persons at high risk of contracting the virus.

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CRISPRing out Host Cell Proteins

In a recent Nature Communications paper titled "Multiplex secretive engineering enhances recombinant protein production and purity", scientists from the Technical University of Denmark and the University of California, San Diego, describe their work to create a...

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The infinite Monkey Cage

To provide some diversion during these trying times, a colleague recommended ‘The infinite Monkey Cage’. Extremely funny British science podcast. There are more than 10 seasons for your pleasure. You will learn and you will laugh. If you like Monty Python you are on...

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COVID-19 vaccines

Hope for containing the COVI-19 pandemic rests on the develop of an effective vaccine for SARS-CoV-2. Recently we found an interesting list of 16 ongoing efforts to develop a SARS-CoV-2 vaccine in the magazine The Scientist. These vaccines vary considerably in their...

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Phage to prevent virus infection

Another potential application for phage that could not be more timely: phage-based particles engineered to envelop virus and prevent virus entry into mammalian cells. A team in Germany and Norway developed modified phage capsid that display sugar moieties to bind...

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