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Biologics

Phage to prevent virus infection

Another potential application for phage that could not be more timely: phage-based particles engineered to envelop virus and prevent virus entry into mammalian cells. A team in Germany and Norway developed modified phage capsid that display sugar moieties to bind...

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Who’s afraid of IgM?

Immunoglobulin M (IgM) is the second most common antibody in humans surpassed only by immunoglobulin G (IgG). The IgM molecule is a pentamer - whereas IgG is a dimer - and with a molecular weight of appr. 900,000 D IgM has more than 5 times the molecular weight of...

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Monoclonals for migraine

Exciting news regarding a new indication for monoclonal antibodies. FDA has approved Aimovig, a product of the Amgen and Novartis Neuroscience Collaboration, for the prevention of frequent, debilitating migraines.  Aimovig is a human immunoglobulin G2 monoclonal...

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Monoclonals for dogs

If your dog needs itch relief, your vet may now offer a drug called Cytopoint. Cytopoint, produced by Zoetis Inc. and available in the US since early 2018, is an engineered (caninized) monoclonal antibody directed against interleukin-31. Interleukin-31 has been shown...

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