858-449-1310 contact@somatek.com

Biologics

ADC to Help People with Sickle Cell

Sickle cell disease is a set of genetic conditions where abnormalities in the structure of hemoglobin cause red blood cells to take on a long, curved, sickle-like shape, which can then impede blood flow. Gene therapies may make a huge difference in the lives of...

read more

Nobel Prize Awarded for mRNA Vaccines against COVID

The 2023 Nobel Prize in Physiology or Medicine was announced today, and has been awarded to Drs. Karolin Karikó and Drew Weissman for their “discoveries concerning nucleoside base modifications that enabled the development of effective mRNA vaccines against COVID-19”....

read more

D is for DNase

This year marks 30 years since the approval of the biologic dornase alfa, a recombinant DNA degrading enzyme for the treatment of cystic fibrosis. Dornase alfa is a recombinant human deoxyribonuclease I (rhDNase) which selectively cleaves DNA and degrades...

read more

C is for Checkpoint Inhibitors

Immune checkpoints are a normal part of the immune system. They prevent an immune response from being so strong that it destroys healthy cells. Immune checkpoints engage when proteins on the surface of T cells recognize and bind to partner proteins on other cells,...

read more

Ozempic: A Blockbuster Biologic

Semaglutide, the diabetes and weight-loss drug marketed under the names Ozempic, Wegovy, and Rybelsus, has gotten a lot of attention recently due to shortages arising from increased demand. Ozempic and Wegovy are both manufactured by the Danish pharmaceutical company...

read more

B is for Biosimilars

A biosimilar, per FDA, is a biologic medication that is highly similar to and has no clinically meaningful differences from an existing FDA-approved biologic, called a reference product. Compared with a reference product, biosimilars: are made with the same types of...

read more

A is for Antibodies

Let’s start our series Biologics A – Z very appropriately with A for antibodies. Antibodies, or more specifically immunoglobulins based on the sturdy mouse and human immunoglobulins of the IgG subclass, are a major biologics workhorse. They have found wide application...

read more

See you at BPI West

Somatek is attending 2023 BioProcess International US West. The conference takes place from February 27 - March 2 at the San Diego Convention Center under the headline ACCELERATE SPEED TO MARKET FOR YOUR NEXT GENERATION MABS, VACCINES AND CELL/GENE THERAPY PRODUCTS....

read more

CYTOSYS Bioreactor Controller

This post and a huge thank you to David Sergeant and Justin Foox of Ipratech has been overdue for some time. Early last year, Somatek acquired a CYTOSYS control platform for its process development work. Having experience with bioreactor controllers from several other...

read more