858-449-1310 contact@somatek.com

Biologics

Tiny bovine antibody fragments show big potential

In the world of monoclonal antibodies, being small is a big deal. Smaller antibodies and antibody fragments can penetrate solid tumors that would be inaccessible to larger antibodies, and some can even make it across the blood-brain barrier. That’s why it’s exciting that researchers at the University of Bath and UCB (a Belgian biotech company) have designed extra-small antibody fragments from cows.

read more

Novel fusion protein could help hemophilia A patients

Hemophilia A, a rare medical condition that prevents blood from clotting properly, may soon have a new therapy to contend with, courtesy of a team led by hematologist Barbara Konkle of Bloodworks Northwest. A new fusion protein based on factor VIII has shown promising results in a small-scale clinical trial and has some researchers hopeful that this novel therapy could make life easier for hemophilia A patients.

read more

mAbs: The Rory Story

My family’s dog, Rory, has always been weird. He will start screaming if, while running around the house like a maniac, he accidentally stubs his toe. He loves eating carrots. He gets jealous if two people are hugging and he isn’t included. He will only lie down on the softest pillow on the couch. He likes to sit on our laps after we’ve eaten dinner and flops over with wild abandon, confident that someone will catch him before he falls. He has been known to collect items such as books, shoes, and pencils in a particular corner of the living room. He is exceptionally food motivated and sometimes obnoxious in his relentless pursuit of affection.

read more

Super-antibodies against SARS-CoV-2 show promising results in animals

If you’ve been following biomedical news on the novel coronavirus over the last several months, there’s a good chance you’ve heard about the potential for antibodies from recovered COVID-19 patients (convalescent antibodies) to help fight the virus and provide temporary immunity to healthcare workers and other persons at high risk of contracting the virus.

read more

CRISPRing out Host Cell Proteins

In a recent Nature Communications paper titled "Multiplex secretive engineering enhances recombinant protein production and purity", scientists from the Technical University of Denmark and the University of California, San Diego, describe their work to create a...

read more

The infinite Monkey Cage

To provide some diversion during these trying times, a colleague recommended ‘The infinite Monkey Cage’. Extremely funny British science podcast. There are more than 10 seasons for your pleasure. You will learn and you will laugh. If you like Monty Python you are on...

read more

COVID-19 vaccines

Hope for containing the COVI-19 pandemic rests on the develop of an effective vaccine for SARS-CoV-2. Recently we found an interesting list of 16 ongoing efforts to develop a SARS-CoV-2 vaccine in the magazine The Scientist. These vaccines vary considerably in their...

read more