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California Insulin

About 8 million Americans with diabetes take insulin, a peptide hormone, to regulate their blood sugar. Those without health insurance, or who have high-deductible plans, often spend hundreds of dollars a month on this life-saving medication, and one 2019 study found...

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Structural Biology in the time of AI

Last year, DeepMind Technologies released predictions for the shape of more than 350,000 proteins, including every protein expressed by the human genome, using its AI tool AlphaFold. Now, they've expanded the publicly available database to more than 200 million...

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BioRad-Explorer: Tools for Science Education

BioRad Laboratories is celebrating 25 years of BioRad Explorer. The Bio-Rad Explorer program has collaborated with educators, researchers, and industry to bring innovative educational kits and state-of-the-art equipment and reagents into classrooms around the world....

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Do Cancer Cells Sleep at Night?

The circadian rhythm influences bodily functions in health and disease. The study of biological cycles driven by environmental and genetic factors is an emerging field and some circadian aspects of metabolism have received considerable attention by the public (looking...

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Biosimilars

Biologics, especially antibodies, are important cancer therapeutics that have significantly improved outcomes for a number of solid tumors. However, biologics are considerably more costly than small-molecule drugs; in part because they are more complex to manufacture,...

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Metformin Linked to Birth Defects

Metformin is, under brand name Glucophage, a well-established drug to treat type 2 diabetes.  Oncology also has an interest in metformin as observational studies suggest a survival benefit for people with hormone dependent cancers, including ovarian, breast and...

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Standard Time 0 – 2 Daylight Saving

Just recently Californians suffered again through the switch to daylight saving time. Although in 2018, 60% of California voters supported Proposition 7, which would give lawmakers the power to end the switching of the clocks, the gears of government are working...

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New Approvals for Cancer Treatments

In 2021, FDA approved more than 60 oncology drugs and biologics including dangling accelerated Approvals, drug dosing, new approvals and more. This recently published article coauthored by FDA’s Steven Lemery and Richard Pazdur provides a nice summary of FDA...

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Progress Towards Universal Influenza Vaccine

Influenza vaccines typically coax the immune system to generate antibodies that recognize the head of hemagglutinin (HA), a protein that extends outward from the surface of the flu virus. The head is the most accessible regions of HA, making it a good target for the...

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